Package: chlorpromazineR 0.2.0

Eric Brown

chlorpromazineR: Convert Antipsychotic Doses to Chlorpromazine Equivalents

As different antipsychotic medications have different potencies, the doses of different medications cannot be directly compared. Various strategies are used to convert doses into a common reference so that comparison is meaningful. Chlorpromazine (CPZ) has historically been used as a reference medication into which other antipsychotic doses can be converted, as "chlorpromazine-equivalent doses". Using conversion keys generated from widely-cited scientific papers, e.g. Gardner et. al 2010 <doi:10.1176/appi.ajp.2009.09060802> and Leucht et al. 2016 <doi:10.1093/schbul/sbv167>, antipsychotic doses are converted to CPZ (or any specified antipsychotic) equivalents. The use of the package is described in the included vignette. Not for clinical use.

Authors:Eric Brown [aut, cre], Parita Shah [aut], Julia Kim [aut], Frederick Boehm [rev]

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NEWS

# Install 'chlorpromazineR' in R:
install.packages('chlorpromazineR', repos = c('https://ropensci.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/ropensci/chlorpromaziner/issues

Datasets:
  • davis1974 - Chlorpromazine equivalent key from Davis 1974 data
  • gardner2010 - Chlorpromazine equivalent key from Gardner et al. 2010 data
  • gardner2010_withsai - Chlorpromazine equivalent key from Gardner et al. 2010 data
  • leucht2016 - Chlorpromazine equivalent key from Leucht et al. 2016 data
  • leucht2020 - Antipsychotic equivalent key from Leucht et al. 2020 data
  • woods2003 - Chlorpromazine equivalent key from Woods 2003 data

On CRAN:

antipsychoticpharmacologypsychiatryschizophrenia

6 exports 12 stars 1.59 score 0 dependencies 164 downloads

Last updated 3 years agofrom:6fa5e312f8 (on master)

Exports:add_keycheck_apcheck_keyto_apto_cpztrim_key

Dependencies:

Examples produced by chlorpromazineR

Rendered fromexampletable.Rmdusingknitr::rmarkdownon Jul 16 2024.

Last update: 2021-03-13
Started: 2021-02-14

Using chlorpromazineR to calculate chlorpromazine-equivalent doses

Eric Brown, Parita Shah, Julia Kim

Rendered fromwalkthrough.Rmdusingknitr::rmarkdownon Jul 16 2024.

Last update: 2021-03-13
Started: 2019-03-29